Your research digest
Monday 26 October 2026 · 3 new papers
Efficacy and safety of relfovetmab administered every three months for the treatment of pain associated with osteoarthritis in client-owned cats
The Veterinary Journal · 2 Oct 2026 · doi:10.1016/j.tvjl.2026.106909
A placebo-controlled field trial in 307 client-owned cats with osteoarthritis tested relfovetmab, an anti-NGF antibody injected every three months. At day 90, 73% of treated cats met the owner-rated success criterion versus 47% on placebo, with benefits from day 3 through nine months. Adverse events were similar between groups apart from more pain on injection.
Why this is for you: Anti-NGF therapy for feline OA pain with a three-monthly dosing schedule.
Relevant · Not relevant
Intra-articular 2.5% polyacrylamide hydrogel provides sustained clinical improvement over 1 year in canine elbow osteoarthritis
Journal of the American Veterinary Medical Association · 21 Oct 2026 · doi:10.2460/javma.26.05.0435
Eighteen dogs with CT-confirmed elbow osteoarthritis received an intra-articular polyacrylamide hydrogel injection and were followed for a year. Owner-reported pain, clinician pain scales, range of motion and joint effusion all improved from 3 to 12 months, with only minor, self-limiting side effects. The study was small and had no control group.
Why this is for you: One-year outcomes of an injectable OA treatment, measured with CBPI and Glasgow pain scales.
Relevant · Not relevant
Placebo-controlled randomized clinical study using a collagen hydrolysate-enriched diet in dogs with osteoarthritis
The Veterinary Journal · 24 Oct 2026 · doi:10.1016/j.tvjl.2026.106946
In a 12-week double-blind trial, 45 dogs with mild osteoarthritis ate either a collagen hydrolysate-enriched diet or a matched placebo diet. Owner questionnaires and force-plate gait analysis showed no difference between groups; both improved, pointing to a caregiver placebo effect. Nine dogs dropped out, and the sample was small and mixed.
Why this is for you: A negative RCT on a dietary OA intervention, useful when owners ask about supplements.
Relevant · Not relevant